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Citalopram prehistory

The citalopram drug is today the best-selling antidepressant in Germany. The active ingredient Citalopram was developed in 1989 by the Danish pharmaceutical company Lundbeck. It was not until 1996 that the drug was approved in Germany.
When the patent of H. Lundbeck A / S expired in 2003, imitations (generics) came onto the market. Generics are products that contain the same active pharmaceutical ingredient in quantity and pharmaceutical form as the original preparation. The main difference is the excipients. However, the copies of the same type are significantly cheaper than the original Cipramil.

Citalopram is a psychotropic drug (antidepressant) and available on the market under various names. Citalopram belongs to the group of selective serotonin reuptake inhibitors SSRI.
Serotonin reuptake inhibitors act on the serotonin metabolism by blocking the cell transporters that transport the serotonin back to the cells of origin. This leads to an increase in the neurotransmitter concentration in the synaptic cleft between two cells and to a mood-lightening and anxiolytic effect. The patient perceives the experience differently in this way, so that he can lead a nearly normal life. But as with any other drug, Citalopram also has side effects and potential dangers. For example, there are not enough insights into the potential risks of taking citalopram during pregnancy. Therefore, the drug should not be taken during pregnancy and if so, then only if clearly necessary and after careful consideration of benefits and risks by the treating physician. Also risky is the concomitant use of alcohol and certain pre-existing conditions. Anyone who is taking other medicines because of these diseases must expect that they will interact with citalopram. Caution is advised in patients who are suicidal. In the first few weeks, even before the drug is fully effective, there is a willingness to become more active. In this time it can come increasingly to suicidal thoughts and also …

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Original Language of Article: German
Website language Original: Germann
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